Immune Regulation by helminth parasites: cellular and molecular mechanisms
نویسندگان
چکیده
منابع مشابه
Regulation of the host immune system by helminth parasites
Helminth parasite infections are associated with a battery of immunomodulatory mechanisms that affect all facets of the host immune response to ensure their persistence within the host. This broad-spectrum modulation of host immunity has intended and unintended consequences, both advantageous and disadvantageous. Thus the host can benefit from suppression of collateral damage during parasite in...
متن کاملMolecular and cellular biology of helminth parasites IV.
FOR ORAL PRESENTATIONS Nematode genomics and informatics: leveraging C. elegans PAUL W. STERNBERG. CALIFORNIA INSTITUTE OF TECHNOLOGY, PASADENA, CA HHMI, Caltech and WormBase C. elegans has emerged as a model organism, not only for classical biology but also for genomics and bioinformatics. With the emergence of additional genome informatic resources, the C. elegans and parasitic helminth commu...
متن کاملImmunomodulation by helminth parasites: defining mechanisms and mediators.
Epidemiological and interventional human studies, as well as experiments in animal models, strongly indicate that helminth parasitic infections can confer protection from immune dysregulatory diseases such as allergy, autoimmunity and colitis. Here, we review the immunological pathways that helminths exploit to downregulate immune responses, both against bystander specificities such as allergen...
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متن کاملImmune Regulation during Helminth Infections
Helminth is a nonphylogenetic term that refers to multicellular animals (or metazoans) that have adopted a parasitic lifestyle in mammalian hosts. They are more commonly referred to as parasitic worms. These worms generally (with the exception of Strongyloides stercoralis) cannot replicate within the host, and they have evolved distinct methods to co-exist with their host through the activation...
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2003
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri1183